| Date | Location | Result | |
| Dec 21, 2021 | Frisco, Texas | San Diego St. 38, UTSA 24 | Box score |
| Dec 03, 2021 | San Antonio, Texas | UTSA 49, WKU 41 | Box score |
| Nov 27, 2021 | Denton, Texas | North Texas 45, UTSA 23 | Box score |
| Nov 20, 2021 | San Antonio, Texas | UTSA 34, UAB 31 | Box score |
| Nov 13, 2021 | San Antonio, Texas | UTSA 27, Southern Miss 17 | Box score |
| Nov 06, 2021 | El Paso, Texas | UTSA 44, UTEP 23 | Box score |
| Oct 23, 2021 | Ruston, Louisiana | UTSA 45, Louisiana Tech 16 | Box score |
| Oct 16, 2021 | San Antonio, Texas | UTSA 45, Rice 0 | Box score |
| Oct 09, 2021 | Bowling Green, Ky. | UTSA 52, WKU 46 | Box score |
| Oct 02, 2021 | San Antonio, Texas | UTSA 24, UNLV 17 | Box score |
| Sep 25, 2021 | Memphis, Tennessee | UTSA 31, Memphis 28 | Box score |
| Sep 18, 2021 | San Antonio, Texas | UTSA 27, Middle Tennessee 13 | Box score |
| Sep 11, 2021 | San Antonio, Texas | UTSA 54, Lamar 0 | Box score |
| Sep 04, 2021 | Champaign, Illinois | UTSA 37, Illinois 30 | Box score |