| Date | Location | Result | |
| 03/09/22 | Frisco, TX | Old Dominion 65, UTSA 45 | Box score |
| 03/08/22 | Frisco, TX | UTSA 58, UTEP 57 (OT) | Box score |
| 03/05/22 | Houston, TX | Rice 86, UTSA 48 | Box score |
| 03/03/22 | Denton, TX | North Texas 53, UTSA 51 | Box score |
| 02/23/22 | Birmingham, AL | UAB 57, UTSA 50 | Box score |
| 02/19/22 | San Antonio, TX | UTSA 59, Louisiana Tech 49 | Box score |
| 02/17/22 | San Antonio, TX | Southern Miss. 66, UTSA 50 | Box score |
| 02/13/22 | Bowling Green, KY | Western Ky. 81, UTSA 70 | Box score |
| 02/07/22 | Hattiesburg, MS | Southern Miss. 60, UTSA 57 (OT) | Box score |
| 02/05/22 | San Antonio, TX | North Texas 70, UTSA 57 | Box score |
| 01/29/22 | Boca Raton, FL | UTSA 49, Fla. Atlantic 44 | Box score |
| 01/27/22 | Miami, FL | FIU 81, UTSA 53 | Box score |
| 01/23/22 | El Paso, TX | UTEP 71, UTSA 59 | Box score |
| 01/20/22 | San Antonio, TX | UTEP 69, UTSA 52 | Box score |
| 01/17/22 | Ruston, LA | Louisiana Tech 79, UTSA 64 | Box score |
| 01/15/22 | San Antonio, TX | Charlotte 58, UTSA 33 | Box score |
| 01/13/22 | San Antonio, TX | Old Dominion 57, UTSA 46 | Box score |
| 01/01/22 | San Antonio, TX | UTSA 68, UAB 60 (OT) | Box score |
| 12/30/21 | San Antonio, TX | Middle Tenn. 85, UTSA 56 | Box score |
| 12/20/21 | Bryan-College Station, TX | Texas A&M 77, UTSA 51 | Box score |
| 12/18/21 | South Padre Island, TX | Grand Canyon 62, UTSA 52 | Box score |
| 12/17/21 | Edinburg, TX | UTSA 66, UTRGV 59 | Box score |
| 12/13/21 | San Antonio, TX | UTSA 49, Dartmouth 39 | Box score |
| 12/05/21 | Tempe, AZ | Colorado St. 52, UTSA 48 | Box score |
| 12/04/21 | Tempe, AZ | Arizona St. 68, UTSA 44 | Box score |
| 11/28/21 | Minneapolis, MN | Minnesota 81, UTSA 52 | Box score |
| 11/21/21 | San Antonio, TX | UTSA 66, Incarnate Word 60 | Box score |
| 11/18/21 | San Antonio, TX | Texas St. 76, UTSA 62 | Box score |
| 11/13/21 | Abilene, TX | Abilene Christian 72, UTSA 53 | Box score |
| 11/09/21 | San Antonio, TX | SFA 77, UTSA 50 | Box score |